Hotels in Santa Croce, Venice

Santa Croce is a sestiere—one of the six historic districts of Venice. Its name derives from the Santa Croce church, dating from the 14th century, though the current structure is largely 19th-century. The district is anchored by the Piazzale Roma—the main entry point for road and bus traffic into the city—and the Santa Lucia railway station.

This area offers a mix of residential calm and major transport hubs. Beyond the parking garages and terminals, you'll find the notable San Simeone Piccolo church, the Fondaco dei Turchi museum, and the modern Calatrava Bridge (Ponte della Costituzione). It serves as a practical gateway for exploring the rest of Venice.