Hotels in Florence
Curated collection coming soon
Browse hotels in Florence, South Carolina, where I-95 meets I-20. Properties sit minutes from the Florence Museum and Francis Marion University.
Photo by Ilse Orsel on Unsplash
About Florence
Florence: Pee Dee Crossroads and Regional Hub
Florence, South Carolina sits at the junction of I-95 and I-20, one of the Southeast's busiest highway intersections. The city anchors the Pee Dee region, a stretch of coastal plain roughly 80 miles northeast of Columbia. Founded as a railroad depot town in 1853, Florence grew into a regional medical and commercial center serving a six-county area of about 200,000 residents.
The Florence Museum, established in 1924, holds collections of South Carolina art and Pacific Rim artifacts — one of the state's oldest civic museums. Francis Marion University brings academic visitors to the city's west side. The Florence Motor Speedway on TV Road has featured Nascar drivers on its short-track schedule, drawing regional racing fans on event weekends.
Practical Tips
- Getting around: A car is essential; no intercity rail serves Florence, and Greyhound covers limited routes.
- Climate: Summers average above 90 °F with high humidity; spring and fall offer milder temperatures.
- Airport: Florence Regional Airport (FLO) handles limited regional flights; Columbia Metropolitan (CAE) sits 80 miles west via I-20.
- Booking timing: Hotel rates spike during Southeastern sporting events and I-95 holiday travel — reserve at least two weeks ahead.
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