Don Gregorio Spa

Around the foothills of the Sierra de los Comechingones, Don Gregorio Spa takes advantage of Merlo's standing as one of Argentina's foremost wellness destinations — the valley's negatively ionized air draws visitors from Buenos Aires throughout the year.

The property pairs its spa facilities with accommodation that earns a 9.7 guest rating across 39 reviews, placing it among the highest-scored addresses in San Luis province. Rooms face the sierra rather than the street, keeping ambient noise low.

Merlo sits at roughly 900 metres elevation, shielding the valley from Pampas heat. The town centre and its artisan market are a short walk from Neptuno 455, while trekking routes into the Comechingones range begin within two kilometres of the property.